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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'SRSF protein kinase 1' and Ligand = 'BDBM101831'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
SRSF protein kinase 1


(Homo sapiens (Human))
BDBM101831
PNG
(US9695160, 44 | US9796707, Compound 44)
Show SMILES FC(F)(F)c1ccc(N2CCN(Cc3ccccn3)CC2)c(NC(=O)c2ncn[nH]2)c1
Show InChI InChI=1S/C20H20F3N7O/c21-20(22,23)14-4-5-17(16(11-14)27-19(31)18-25-13-26-28-18)30-9-7-29(8-10-30)12-15-3-1-2-6-24-15/h1-6,11,13H,7-10,12H2,(H,27,31)(H,25,26,28)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 8.41E+3n/an/an/an/an/an/a



The University of Nottingham; NewSouth Innovations PTY Limited

US Patent


Assay Description
Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....


US Patent US9796707 (2017)


BindingDB Entry DOI: 10.7270/Q2125VTM
More data for this
Ligand-Target Pair
SRSF protein kinase 1


(Homo sapiens (Human))
BDBM101831
PNG
(US9695160, 44 | US9796707, Compound 44)
Show SMILES FC(F)(F)c1ccc(N2CCN(Cc3ccccn3)CC2)c(NC(=O)c2ncn[nH]2)c1
Show InChI InChI=1S/C20H20F3N7O/c21-20(22,23)14-4-5-17(16(11-14)27-19(31)18-25-13-26-28-18)30-9-7-29(8-10-30)12-15-3-1-2-6-24-15/h1-6,11,13H,7-10,12H2,(H,27,31)(H,25,26,28)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 8.41E+3n/an/an/an/an/a30



The University of Nottingham; NewSouth Innovations PTY Limited

US Patent


Assay Description
Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....


US Patent US9695160 (2017)


BindingDB Entry DOI: 10.7270/Q2639MW1
More data for this
Ligand-Target Pair