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Found 1 hit Enz. Inhib. hit(s) with Target = 'STAM-binding protein' and Ligand = 'BDBM50514117'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
STAM-binding protein


(Homo sapiens (Human))		BDBM50514117
PNG
(CHEMBL4586347)
Show SMILES O=C(CSc1nc2ccc(cc2c(=O)n1CCc1ccccc1)N1CCOCC1)NCc1ccco1
Show InChI InChI=1S/C27H28N4O4S/c32-25(28-18-22-7-4-14-35-22)19-36-27-29-24-9-8-21(30-12-15-34-16-13-30)17-23(24)26(33)31(27)11-10-20-5-2-1-3-6-20/h1-9,14,17H,10-13,15-16,18-19H2,(H,28,32)
PDB

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MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 330n/an/an/an/an/an/a



Dana-Farber Cancer Institute

Curated by ChEMBL


Assay Description
Inhibition of human STAMBP expressed in Sf21 cells pre-incubated for 20 mins before Ubiquitinated NALP7 substrate addition and measured after 1 hr by...

J Med Chem 63: 2731-2750 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01138
BindingDB Entry DOI: 10.7270/Q2GF0XTC
More data for this
Ligand-Target Pair