Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sepiapterin reductase (Homo sapiens (Human)) | BDBM50515146 (CHEMBL4582418) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Gr�nenthal GmbH Curated by ChEMBL | Assay Description Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysis | J Med Chem 62: 6391-6397 (2019) Article DOI: 10.1021/acs.jmedchem.9b00218 BindingDB Entry DOI: 10.7270/Q2JW8J6W | |||||||||||
More data for this Ligand-Target Pair |