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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sepiapterin reductase' and Ligand = 'BDBM50537634'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sepiapterin reductase


(Homo sapiens (Human))		BDBM50537634
PNG
(CHEMBL4639502)
Show SMILES FC(F)(F)Oc1cccc(c1)-n1nnnc1N1CCN(CC1)c1ncnc2sc3CCCc3c12
Show InChI InChI=1S/C21H19F3N8OS/c22-21(23,24)33-14-4-1-3-13(11-14)32-20(27-28-29-32)31-9-7-30(8-10-31)18-17-15-5-2-6-16(15)34-19(17)26-12-25-18/h1,3-4,11-12H,2,5-10H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7.59E+3n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells

Bioorg Med Chem Lett 30: (2020)


Article DOI: 10.1016/j.bmcl.2019.126793
BindingDB Entry DOI: 10.7270/Q2Z89G99
More data for this
Ligand-Target Pair