Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sepiapterin reductase' and Ligand = 'BDBM50537649'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sepiapterin reductase (Homo sapiens (Human))	BDBM50537649 (CHEMBL1723285) Show SMILES Cc1nn(CCO)c2ncc(cc12)C(=O)c1cc(F)ccc1O Show InChI InChI=1S/C16H14FN3O3/c1-9-12-6-10(8-18-16(12)20(19-9)4-5-21)15(23)13-7-11(17)2-3-14(13)22/h2-3,6-8,21-22H,4-5H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Epidermal growth factor receptor autophosphorylation in A431 human epidermoid carcinoma cells				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126793 BindingDB Entry DOI: 10.7270/Q2Z89G99
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