Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sepiapterin reductase' and Ligand = 'BDBM50537660'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sepiapterin reductase (Homo sapiens (Human))	BDBM50537660 (CHEMBL4634222) Show SMILES Cc1nn(-c2ccccn2)c2ncc(cc12)C(=O)c1cc(C)ccc1O Show InChI InChI=1S/C20H16N4O2/c1-12-6-7-17(25)16(9-12)19(26)14-10-15-13(2)23-24(20(15)22-11-14)18-5-3-4-8-21-18/h3-11,25H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at CB1 receptor by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126793 BindingDB Entry DOI: 10.7270/Q2Z89G99
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