Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sepiapterin reductase' and Ligand = 'BDBM50537661'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sepiapterin reductase (Homo sapiens (Human))	BDBM50537661 (CHEMBL4648946) Show SMILES Cc1nn(-c2ccccn2)c2ncc(cc12)C(=O)c1cc(F)ccc1O Show InChI InChI=1S/C19H13FN4O2/c1-11-14-8-12(18(26)15-9-13(20)5-6-16(15)25)10-22-19(14)24(23-11)17-4-2-3-7-21-17/h2-10,25H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at CB1 receptor by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126793 BindingDB Entry DOI: 10.7270/Q2Z89G99
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