Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase 4' and Ligand = 'BDBM451724'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase 4 (Homo sapiens (Human))	BDBM451724 (6-(2-amino-5- (benzo[b]thiophen-4- yl)pyridin-3-yl...) Show SMILES Nc1ncc(cc1-c1ccc2C(=O)NCCc2c1)-c1cccc2sccc12 Show InChI InChI=1S/C22H17N3OS/c23-21-19(13-4-5-17-14(10-13)6-8-24-22(17)26)11-15(12-25-21)16-2-1-3-20-18(16)7-9-27-20/h1-5,7,9-12H,6,8H2,(H2,23,25)(H,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
DANA-FARBER CANCER INSTITUTE, INC.; FONDAZIONE CENTRO SAN RAFFAELE US Patent					Assay Description Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...				US Patent US10710978 (2020) BindingDB Entry DOI: 10.7270/Q2J67KZW
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