Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase 4' and Ligand = 'BDBM451739'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase 4 (Homo sapiens (Human))	BDBM451739 (4-(6-amino-5-(1-oxo-1,2,3,4- tetrahydroisoquinolin...) Show SMILES COc1cc(ccc1-c1cnc(N)c(c1)-c1ccc2C(=O)NCCc2c1)S(=O)(=O)NC1CC1 Show InChI InChI=1S/C24H24N4O4S/c1-32-22-12-18(33(30,31)28-17-3-4-17)5-7-19(22)16-11-21(23(25)27-13-16)14-2-6-20-15(10-14)8-9-26-24(20)29/h2,5-7,10-13,17,28H,3-4,8-9H2,1H3,(H2,25,27)(H,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
DANA-FARBER CANCER INSTITUTE, INC.; FONDAZIONE CENTRO SAN RAFFAELE US Patent					Assay Description Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...				US Patent US10710978 (2020) BindingDB Entry DOI: 10.7270/Q2J67KZW
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