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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase 4' and Ligand = 'BDBM451744'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase 4


(Homo sapiens (Human))		BDBM451744
PNG
(6-(2-amino-5-(2-fluoro-4- nitrophenyl)pyridin-3-yl...)
Show SMILES Nc1ncc(cc1-c1ccc2C(=O)NCCc2c1)-c1ccc(cc1F)[N+]([O-])=O
Show InChI InChI=1S/C20H15FN4O3/c21-18-9-14(25(27)28)2-4-15(18)13-8-17(19(22)24-10-13)11-1-3-16-12(7-11)5-6-23-20(16)26/h1-4,7-10H,5-6H2,(H2,22,24)(H,23,26)
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a 120n/an/an/an/an/an/a



DANA-FARBER CANCER INSTITUTE, INC.; FONDAZIONE CENTRO SAN RAFFAELE

US Patent


Assay Description
Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...

US Patent US10710978 (2020)


BindingDB Entry DOI: 10.7270/Q2J67KZW
More data for this
Ligand-Target Pair