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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase 4' and Ligand = 'BDBM451757'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase 4


(Homo sapiens (Human))		BDBM451757
PNG
(N-(4-(6-amino-5-(1-oxo- 1,2,3,4-tetrahydroisoquino...)
Show SMILES CC(C)Oc1cc(NS(=O)(=O)C2CC2)ccc1-c1cnc(N)c(c1)-c1ccc2C(=O)NCCc2c1
Show InChI InChI=1S/C26H28N4O4S/c1-15(2)34-24-13-19(30-35(32,33)20-5-6-20)4-8-21(24)18-12-23(25(27)29-14-18)16-3-7-22-17(11-16)9-10-28-26(22)31/h3-4,7-8,11-15,20,30H,5-6,9-10H2,1-2H3,(H2,27,29)(H,28,31)
PDB

UniProtKB/SwissProt

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PC cid
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US Patent
n/an/a<40n/an/an/an/an/an/a



DANA-FARBER CANCER INSTITUTE, INC.; FONDAZIONE CENTRO SAN RAFFAELE

US Patent


Assay Description
Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...

US Patent US10710978 (2020)


BindingDB Entry DOI: 10.7270/Q2J67KZW
More data for this
Ligand-Target Pair