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Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase 4' and Ligand = 'BDBM451764'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase 4


(Homo sapiens (Human))		BDBM451764
PNG
(6-(2-amino-5-(4- chlorothiazol-5-yl)pyridin-3- yl)...)
Show SMILES CN1CCc2cc(ccc2C1=O)-c1cc(cnc1N)-c1cccc2ncsc12
Show InChI InChI=1S/C22H18N4OS/c1-26-8-7-14-9-13(5-6-17(14)22(26)27)18-10-15(11-24-21(18)23)16-3-2-4-19-20(16)28-12-25-19/h2-6,9-12H,7-8H2,1H3,(H2,23,24)
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a 120n/an/an/an/an/an/a



DANA-FARBER CANCER INSTITUTE, INC.; FONDAZIONE CENTRO SAN RAFFAELE

US Patent


Assay Description
Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...

US Patent US10710978 (2020)


BindingDB Entry DOI: 10.7270/Q2J67KZW
More data for this
Ligand-Target Pair