Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase B-raf' and Ligand = 'BDBM107673'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM107673 (1-(3-(6-Chloro-2-methylpyrimidin-4-ylamino)phenyl)...) Show SMILES Cc1nc(Cl)cc(Nc2cccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)c2)n1 Show InChI InChI=1S/C19H14Cl2F3N5O/c1-10-25-16(21)9-17(26-10)27-11-3-2-4-12(7-11)28-18(30)29-13-5-6-15(20)14(8-13)19(22,23)24/h2-9H,1H3,(H,25,26,27)(H2,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	722	n/a	n/a	n/a	n/a	7.5	25
Shanghai Institute of Pharmaceutical Industry, 1111 Zhongshan North One Road, Hongkou District, Shanghai, 200437, China					Assay Description Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...				Chem Biol Drug Des 83: 27-36 (2014) Article DOI: 10.1111/cbdd.12198 BindingDB Entry DOI: 10.7270/Q2VH5MHM
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