Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase B-raf' and Ligand = 'BDBM50311993'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50311993 (3-(4-fluoro-3-methoxyphenyl)-7-(2-methyl-4-((1S,4S...) Show SMILES COc1cc(ccc1F)-c1c(nn2c(ccnc12)-c1ccc(cc1C)N1C[C@@H]2C[C@H]1CN2C)-c1ccncc1 |r| Show InChI InChI=1S/C31H29FN6O/c1-19-14-22(37-18-23-16-24(37)17-36(23)2)5-6-25(19)27-10-13-34-31-29(21-4-7-26(32)28(15-21)39-3)30(35-38(27)31)20-8-11-33-12-9-20/h4-15,23-24H,16-18H2,1-3H3/t23-,24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human recombinant B-Raf expressed in Sf9 cells assessed as inhibition of Mek1 phosphorylation				Bioorg Med Chem Lett 19: 6571-4 (2009) Article DOI: 10.1016/j.bmcl.2009.10.030 BindingDB Entry DOI: 10.7270/Q29Z9510
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