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Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase B-raf' and Ligand = 'BDBM50457809'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase B-raf


(Mus musculus)		BDBM50457809
PNG
(CHEMBL4209989)
Show SMILES COc1ccc(CC(=O)Nc2cnn(c2)-c2ccccc2)cc1OC
Show InChI InChI=1S/C19H19N3O3/c1-24-17-9-8-14(10-18(17)25-2)11-19(23)21-15-12-20-22(13-15)16-6-4-3-5-7-16/h3-10,12-13H,11H2,1-2H3,(H,21,23)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 730n/an/an/an/an/an/a



Nanjing University

Curated by ChEMBL


Assay Description
Inhibition of full-length GST-tagged mouse BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...

Bioorg Med Chem Lett 28: 2382-2390 (2018)


Article DOI: 10.1016/j.bmcl.2018.06.028
BindingDB Entry DOI: 10.7270/Q2TM7DQ9
More data for this
Ligand-Target Pair