Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase B-raf [416-766,V600E]' and Ligand = 'BDBM322531'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase B-raf [416-766,V600E] (Homo sapiens (Human))	BDBM322531 (5-[3-[5-(3-chlorophenyl)-1H-imidazol-2-yl]chroman-...) Show SMILES Clc1cccc(c1)-c1cnc([nH]1)C1COc2ccc(Oc3ccnc4NC(=O)CCc34)cc2C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent					Assay Description To determine whether compounds bind to RAF kinases, they are tested in a competition binding assay. The Invitrogen LanthaScreen Eu binding assay invo...				US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair