Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Chk1' and Ligand = 'BDBM411513'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM411513 (Ethyl (R)-1-((6-(3- methylmorpholino)-2- (1H-pyrro...) Show SMILES CCOC(=O)N1CCS(=O)(CC1)=Nc1cc(nc(n1)-c1ccnc2[nH]ccc12)N1CCOC[C@H]1C |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System; ChemPartner Corporation US Patent					Assay Description Inhibitors of ATR kinase are effective at inhibiting the ATR-driven phosphorylation of the downstream target Chk1 kinase at Serine 345, following the...				US Patent US10800769 (2020) BindingDB Entry DOI: 10.7270/Q2XD14R1
					More data for this Ligand-Target Pair