Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Chk2' and Ligand = 'BDBM33214'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM33214 (pyrazolopyridine, 13) Show SMILES NCC1CN(CCO1)c1c(cnc2[nH]ncc12)-c1ccsc1 Show InChI InChI=1S/C15H17N5OS/c16-5-11-8-20(2-3-21-11)14-12(10-1-4-22-9-10)6-17-15-13(14)7-18-19-15/h1,4,6-7,9,11H,2-3,5,8,16H2,(H,17,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	7.4	23
The Institute of Cancer Research					Assay Description CHK kinase function was measured in a DELFIA assay in order to monitor phosphorylation of a CDC25C peptide using a specific phospho antibody. The enz...				J Med Chem 52: 4810-9 (2009) Article DOI: 10.1021/jm900314j BindingDB Entry DOI: 10.7270/Q27W69KC
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