Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Chk2' and Ligand = 'BDBM50291385'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50291385 (CHEMBL4169171) Show SMILES CC(=O)N\N=C\c1c(C)nn(c1Oc1ccc(cc1)-c1nc2cc(ccc2[nH]1)C(O)=O)-c1ccccc1 Show InChI InChI=1S/C27H22N6O4/c1-16-22(15-28-31-17(2)34)26(33(32-16)20-6-4-3-5-7-20)37-21-11-8-18(9-12-21)25-29-23-13-10-19(27(35)36)14-24(23)30-25/h3-15H,1-2H3,(H,29,30)(H,31,34)(H,35,36)/b28-15+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
National Research Centre Curated by ChEMBL					Assay Description Inhibition of Chk2 (unknown origin) by spectrophotometric analysis				Eur J Med Chem 144: 859-873 (2018) Article DOI: 10.1016/j.ejmech.2017.12.023 BindingDB Entry DOI: 10.7270/Q2KD21F1
					More data for this Ligand-Target Pair