Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Chk2' and Ligand = 'BDBM50292365'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50292365 (CHEMBL4160383) Show SMILES Cc1ccc(cc1)-c1nc(S)nc(Sc2ccc(cc2)-c2nc3cc(ccc3[nH]2)C(N)=O)c1C#N Show InChI InChI=1S/C26H18N6OS2/c1-14-2-4-15(5-3-14)22-19(13-27)25(32-26(34)31-22)35-18-9-6-16(7-10-18)24-29-20-11-8-17(23(28)33)12-21(20)30-24/h2-12H,1H3,(H2,28,33)(H,29,30)(H,31,32,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
National Research Centre Curated by ChEMBL					Assay Description Inhibition of Chk2 (unknown origin) assessed as decrease in Cdc25C phosphorylation at Ser216 by ELISA based spectrophotometric analysis				Eur J Med Chem 146: 687-708 (2018) Article DOI: 10.1016/j.ejmech.2018.01.072 BindingDB Entry DOI: 10.7270/Q2TQ643K
					More data for this Ligand-Target Pair