Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Chk2' and Ligand = 'BDBM50335666'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335666 (4-fluoro-2-(4-((3S,5R)-5-(2-hydroxypropan-2-yl)pyr...) Show SMILES CC(C)(O)[C@H]1C[C@@H](CN1)Nc1nc(nc2ccccc12)-c1cc(F)ccc1O |r| Show InChI InChI=1S/C21H23FN4O2/c1-21(2,28)18-10-13(11-23-18)24-19-14-5-3-4-6-16(14)25-20(26-19)15-9-12(22)7-8-17(15)27/h3-9,13,18,23,27-28H,10-11H2,1-2H3,(H,24,25,26)/t13-,18+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair