Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50119286 (3-Methoxy-7,8-dihydro-6H-5,10-dithia-8-aza-benzo[a...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 82.5 | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Pittsburgh | Assay Description In vitro radiometric kinase assay were conducted using PKD1 from Biomol International, PKD2 from SignalChem and PKD3 Enzo Life Sciences. | BMC Chem Biol 10: 5 (2010) Article DOI: 10.1186/1472-6769-10-5 BindingDB Entry DOI: 10.7270/Q2VQ315D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50119286 (3-Methoxy-7,8-dihydro-6H-5,10-dithia-8-aza-benzo[a...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 82.5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Curated by ChEMBL | Assay Description Inhibition of human recombinant PKD1 after 10 mins by radiometric assay | ACS Med Chem Lett 2: 154-159 (2012) Article DOI: 10.1021/ml100230n BindingDB Entry DOI: 10.7270/Q29G5NTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50119286 (3-Methoxy-7,8-dihydro-6H-5,10-dithia-8-aza-benzo[a...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Curated by ChEMBL | Assay Description Inhibition of PKD1 autophosphorylation at Ser916 in human PMA-induced LNCAP cells by Western blotting | ACS Med Chem Lett 2: 154-159 (2012) Article DOI: 10.1021/ml100230n BindingDB Entry DOI: 10.7270/Q29G5NTR | |||||||||||
More data for this Ligand-Target Pair |