Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PAK 4' and Ligand = 'BDBM50449500'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human))	BDBM50449500 (CHEMBL4171374) Show SMILES Cc1ncc(\C=C2/C(=O)Nc3ccc(cc23)C(=O)N[C@H](CO)c2ccccc2)[nH]1 |r| Show InChI InChI=1S/C22H20N4O3/c1-13-23-11-16(24-13)10-18-17-9-15(7-8-19(17)25-22(18)29)21(28)26-20(12-27)14-5-3-2-4-6-14/h2-11,20,27H,12H2,1H3,(H,23,24)(H,25,29)(H,26,28)/b18-10-/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	114	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of full length human PAK4 using substrate S2 after 60 mins by HTRF assay				Eur J Med Chem 155: 197-209 (2018) Article DOI: 10.1016/j.ejmech.2018.05.051 BindingDB Entry DOI: 10.7270/Q2KD21GG
					More data for this Ligand-Target Pair