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Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PAK 4' and Ligand = 'BDBM50449506'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase PAK 4


(Homo sapiens (Human))		BDBM50449506
PNG
(CHEMBL4174632)
Show SMILES OC[C@@H](NC(=O)c1ccc2NC(=O)\C(=C(/c3ncc[nH]3)c3ccc(cc3)C#N)c2c1)c1ccccc1 |r|
Show InChI InChI=1S/C28H21N5O3/c29-15-17-6-8-19(9-7-17)24(26-30-12-13-31-26)25-21-14-20(10-11-22(21)32-28(25)36)27(35)33-23(16-34)18-4-2-1-3-5-18/h1-14,23,34H,16H2,(H,30,31)(H,32,36)(H,33,35)/b25-24-/t23-/m1/s1
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Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of full length human PAK4 using substrate S2 after 60 mins by HTRF assay

Eur J Med Chem 155: 197-209 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.051
BindingDB Entry DOI: 10.7270/Q2KD21GG
More data for this
Ligand-Target Pair