Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PLK1' and Ligand = 'BDBM190248'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM190248 (US9175357, 5597) Show SMILES CNC(=O)c1cc(c(s1)C(F)(F)F)-c1ccccc1 Show InChI InChI=1S/C13H10F3NOS/c1-17-12(18)10-7-9(8-5-3-2-4-6-8)11(19-10)13(14,15)16/h2-7H,1H3,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	8.0	25
UNIVERSITY OF SOUTH CAROLINA US Patent					Assay Description The buffer composition was 50 mM Tris, 200 mM NaCl, 2.0 mM DTT, and 0.005% Tween 20 (pH 8.0). Fragment ligated inhibitors and comparison peptides to ...				US Patent US9175357 (2015) BindingDB Entry DOI: 10.7270/Q2V40T14
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