Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PLK1' and Ligand = 'BDBM190249'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM190249 (US9175357, 5598) Show SMILES CNC(=O)c1ccc(cc1)-c1noc(C)n1 |w:1.0| Show InChI InChI=1S/C11H11N3O2/c1-7-13-10(14-16-7)8-3-5-9(6-4-8)11(15)12-2/h3-6H,1-2H3,(H,12,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	3.20E+5	n/a	n/a	n/a	n/a	8.0	25
UNIVERSITY OF SOUTH CAROLINA US Patent					Assay Description The buffer composition was 50 mM Tris, 200 mM NaCl, 2.0 mM DTT, and 0.005% Tween 20 (pH 8.0). Fragment ligated inhibitors and comparison peptides to ...				US Patent US9175357 (2015) BindingDB Entry DOI: 10.7270/Q2V40T14
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