Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PLK1' and Ligand = 'BDBM50016495'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM50016495 (CHEMBL3260236) Show SMILES [O-][N+](=O)c1ccccc1\C=C\C(=O)NNC(=O)c1ccc2OCCOc2c1 Show InChI InChI=1S/C18H15N3O6/c22-17(8-6-12-3-1-2-4-14(12)21(24)25)19-20-18(23)13-5-7-15-16(11-13)27-10-9-26-15/h1-8,11H,9-10H2,(H,19,22)(H,20,23)/b8-6+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of PLK1 (unknown origin) using RRRDELMEASFADQEAKV as substrate after 20 mins by liquid scintillation counting analysis				Eur J Med Chem 81: 420-6 (2014) Article DOI: 10.1016/j.ejmech.2014.05.026 BindingDB Entry DOI: 10.7270/Q2ZP47PK
					More data for this Ligand-Target Pair