Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PLK1' and Ligand = 'BDBM50435721'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM50435721 (CHEMBL2392551) Show SMILES CN1CCC(CC1)NC(=O)c1ccc(Nc2ncc3N(C)C(=O)C(F)(F)CN(C4CCCC4)c3n2)cc1C Show InChI InChI=1S/C27H35F2N7O2/c1-17-14-19(8-9-21(17)24(37)31-18-10-12-34(2)13-11-18)32-26-30-15-22-23(33-26)36(20-6-4-5-7-20)16-27(28,29)25(38)35(22)3/h8-9,14-15,18,20H,4-7,10-13,16H2,1-3H3,(H,31,37)(H,30,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Takeda California Curated by ChEMBL					Assay Description Inhibition of PLK1 (unknown origin) using biotin-AGAGTVPESIHSFIGDGLV as substrate by TR-FRET assay				Bioorg Med Chem Lett 23: 3662-6 (2013) Article DOI: 10.1016/j.bmcl.2013.02.083 BindingDB Entry DOI: 10.7270/Q2ST7R8C
					More data for this Ligand-Target Pair