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Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase TBK1' and Ligand = 'BDBM50379370'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase TBK1


(Homo sapiens (Human))		BDBM50379370
PNG
(CHEMBL2011899)
Show SMILES Brc1cnc2nc([nH]c2c1NCC1CCNCC1)-c1ccc(OCCN2CCCCC2)cc1
Show InChI InChI=1S/C25H33BrN6O/c26-21-17-29-25-23(22(21)28-16-18-8-10-27-11-9-18)30-24(31-25)19-4-6-20(7-5-19)33-15-14-32-12-2-1-3-13-32/h4-7,17-18,27H,1-3,8-16H2,(H2,28,29,30,31)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 105n/an/an/an/an/an/a



AstraZeneca R&D Boston

Curated by ChEMBL


Assay Description
Inhibition of recombinant TBK1 using 5FAM-AhxKRRAL(ps)VASLPGL as substrate by microfluidic mobility shift assay

Bioorg Med Chem Lett 22: 2063-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.01.018
BindingDB Entry DOI: 10.7270/Q2WS8V74
More data for this
Ligand-Target Pair