Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM111715'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM111715 (US8618111, F-7) Show SMILES CC(C)CC(=O)NCC1CCN(CC1)c1ncnc(C)c1C#Cc1ccc(N)nc1 Show InChI InChI=1S/C23H30N6O/c1-16(2)12-22(30)26-14-19-8-10-29(11-9-19)23-20(17(3)27-15-28-23)6-4-18-5-7-21(24)25-13-18/h5,7,13,15-16,19H,8-12,14H2,1-3H3,(H2,24,25)(H,26,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	237	n/a	n/a	n/a	n/a	7.5	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...				US Patent US8618111 (2013) BindingDB Entry DOI: 10.7270/Q2FX7838
					More data for this Ligand-Target Pair