Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM174399'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM174399 (US9102670, 1dm) Show SMILES C[C@H]1COCCN1c1nc(N2CCOC[C@@H]2C)c2ccc(nc2n1)-c1ccnc(NC(C)=O)c1 |r| Show InChI InChI=1S/C24H29N7O3/c1-15-13-33-10-8-30(15)23-19-4-5-20(18-6-7-25-21(12-18)26-17(3)32)27-22(19)28-24(29-23)31-9-11-34-14-16(31)2/h4-7,12,15-16H,8-11,13-14H2,1-3H3,(H,25,26,32)/t15-,16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.5	n/a	n/a	n/a	n/a	n/a	25
KUDOS PHARMACEUTICALS LIMITED US Patent					Assay Description The assay used AlphaScreen technology (Gray et al., Analytical Biochemistry, 2003, 313: 234-245) to determine the ability of test compounds to inhibi...				US Patent US9102670 (2015) BindingDB Entry DOI: 10.7270/Q26M35MZ
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