Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM50092775'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50092775 (CHEMBL3586396) Show SMILES CO[C@@H]1CC[C@H](CN2CC(=O)Nc3ncc(nc23)-c2ccc(nc2)C(C)(C)O)CC1 |r,wD:5.5,2.1,(6.68,7.38,;6.68,6.15,;5.34,5.38,;5.34,3.84,;4,3.07,;2.67,3.85,;1.33,3.08,;1.33,1.54,;2.66,.77,;2.66,-.77,;3.73,-1.38,;1.33,-1.54,;,-.77,;-1.33,-1.54,;-2.68,-.77,;-2.68,.77,;-1.33,1.54,;,.77,;-4.01,1.54,;-4.01,3.08,;-5.35,3.85,;-6.68,3.08,;-6.68,1.54,;-5.35,.77,;-8.02,3.85,;-9.08,3.23,;-9.08,4.47,;-8.02,5.08,;2.68,5.39,;4.01,6.15,)| Show InChI InChI=1S/C22H29N5O3/c1-22(2,29)18-9-6-15(10-23-18)17-11-24-20-21(25-17)27(13-19(28)26-20)12-14-4-7-16(30-3)8-5-14/h6,9-11,14,16,29H,4-5,7-8,12-13H2,1-3H3,(H,24,26,28)/t14-,16+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	149	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assay				J Med Chem 58: 5323-33 (2015) Article DOI: 10.1021/acs.jmedchem.5b00626 BindingDB Entry DOI: 10.7270/Q208672F
					More data for this Ligand-Target Pair