Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM50447250'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50447250 (CHEMBL3113389) Show SMILES CNS(=O)(=O)c1cc(ccc1C)-c1nnc(Nc2ccc(OCC(N)=O)cc2)c2ccccc12 Show InChI InChI=1S/C24H23N5O4S/c1-15-7-8-16(13-21(15)34(31,32)26-2)23-19-5-3-4-6-20(19)24(29-28-23)27-17-9-11-18(12-10-17)33-14-22(25)30/h3-13,26H,14H2,1-2H3,(H2,25,30)(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sejong University Curated by ChEMBL					Assay Description Inhibition of mTOR (unknown origin) by KINOMEscan assay				Bioorg Med Chem Lett 24: 835-8 (2014) Article DOI: 10.1016/j.bmcl.2013.12.081 BindingDB Entry DOI: 10.7270/Q23B61MR
					More data for this Ligand-Target Pair