Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM50499380'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50499380 (CHEMBL3735998) Show SMILES Cl.FC(F)(F)c1cc(Nc2c(cnc3ccc(cc23)-c2cnc3ccccc3c2)C(=O)NC2CC2)ccc1N1CCNCC1 Show InChI InChI=1S/C33H29F3N6O/c34-33(35,36)27-17-24(8-10-30(27)42-13-11-37-12-14-42)40-31-25-16-20(22-15-21-3-1-2-4-28(21)38-18-22)5-9-29(25)39-19-26(31)32(43)41-23-6-7-23/h1-5,8-10,15-19,23,37H,6-7,11-14H2,(H,39,40)(H,41,43)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of mTOR (unknown origin) using ULight-4E-BP1 peptide as substrate after 1 hr by lance ultra assay				Bioorg Med Chem 23: 7585-96 (2015) Article DOI: 10.1016/j.bmc.2015.11.003 BindingDB Entry DOI: 10.7270/Q2HD7ZPM
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