Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM106909'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM106909 (US8592455, 280) Show SMILES COc1cc(F)c(c(F)c1)-c1cccc(n1)C(=O)Nc1cnccc1[C@H]1C[C@@H](N)C[C@H](C1)C(F)(F)F |r| Show InChI InChI=1S/C25H23F5N4O2/c1-36-16-10-18(26)23(19(27)11-16)20-3-2-4-21(33-20)24(35)34-22-12-32-6-5-17(22)13-7-14(25(28,29)30)9-15(31)8-13/h2-6,10-15H,7-9,31H2,1H3,(H,34,35)/t13-,14+,15-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Novartis AG US Patent					Assay Description The activity of PIM1, PIM2, and PIM3 is measured using a luciferase-luciferin based ATP detection reagent to quantify ATP depletion resulting from ki...				US Patent US8592455 (2013) BindingDB Entry DOI: 10.7270/Q2FF3R0C
					More data for this Ligand-Target Pair