Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM106924'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM106924 (US8592455, 124) Show SMILES N[C@H]1CCC[C@H](C1)c1ccncc1NC(=O)c1ccc(F)c(n1)-c1c(F)ccc(O)c1F |r,wU:5.7,1.0,(-6,2.69,;-4.67,1.92,;-3.33,2.69,;-2,1.92,;-2,.38,;-3.33,-.39,;-4.67,.38,;-3.33,-1.93,;-4.67,-2.7,;-4.67,-4.24,;-3.33,-5.01,;-2,-4.24,;-2,-2.7,;-.67,-1.93,;.67,-2.7,;.67,-4.24,;2,-1.93,;3.33,-2.69,;4.67,-1.93,;4.67,-.39,;6,.38,;3.33,.38,;2,-.39,;3.33,1.92,;2,2.69,;.67,1.92,;2,4.23,;3.33,5,;4.67,4.23,;6,5.01,;4.67,2.69,;6,1.92,)| Show InChI InChI=1S/C23H21F3N4O2/c24-15-5-7-19(31)21(26)20(15)22-16(25)4-6-17(29-22)23(32)30-18-11-28-9-8-14(18)12-2-1-3-13(27)10-12/h4-9,11-13,31H,1-3,10,27H2,(H,30,32)/t12-,13+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Novartis AG US Patent					Assay Description The activity of PIM1, PIM2, and PIM3 is measured using a luciferase-luciferin based ATP detection reagent to quantify ATP depletion resulting from ki...				US Patent US8592455 (2013) BindingDB Entry DOI: 10.7270/Q2FF3R0C
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