Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM206685'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM206685 (US9260425, 446) Show SMILES CCn1cc(cn1)-c1cc2c(n[nH]c2cn1)-c1cccc(n1)N1CCNC(C)(C)C1 Show InChI InChI=1S/C22H26N8/c1-4-30-13-15(11-25-30)18-10-16-19(12-23-18)27-28-21(16)17-6-5-7-20(26-17)29-9-8-24-22(2,3)14-29/h5-7,10-13,24H,4,8-9,14H2,1-3H3,(H,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0290	n/a	n/a	n/a	n/a	n/a	n/a	7.2	n/a
Genetech, Inc. US Patent					Assay Description PIM-1, PIM-2, and PIM-3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J....				US Patent US9260425 (2016) BindingDB Entry DOI: 10.7270/Q2RR1X3X
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