Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM238491'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM238491 (US9394297, 121 | US9394297, 122) Show SMILES N[C@H]1CCC[C@H](C1)Nc1ccc2cccc(-c3cc4c(CCNC4=O)[nH]3)c2n1 Show InChI InChI=1S/C22H25N5O/c23-14-4-2-5-15(11-14)25-20-8-7-13-3-1-6-16(21(13)27-20)19-12-17-18(26-19)9-10-24-22(17)28/h1,3,6-8,12,14-15,26H,2,4-5,9-11,23H2,(H,24,28)(H,25,27)/t14-,15+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	7.0	22
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9394297 (2016) BindingDB Entry DOI: 10.7270/Q2G44P78
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM238491 (US9394297, 121 | US9394297, 122) Show SMILES N[C@H]1CCC[C@H](C1)Nc1ccc2cccc(-c3cc4c(CCNC4=O)[nH]3)c2n1 Show InChI InChI=1S/C22H25N5O/c23-14-4-2-5-15(11-14)25-20-8-7-13-3-1-6-16(21(13)27-20)19-12-17-18(26-19)9-10-24-22(17)28/h1,3,6-8,12,14-15,26H,2,4-5,9-11,23H2,(H,24,28)(H,25,27)/t14-,15+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	7.0	22
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9394297 (2016) BindingDB Entry DOI: 10.7270/Q2G44P78
					More data for this Ligand-Target Pair