Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM376685'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM376685 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)-c1c(F)cc(O)cc1F |r| Show InChI InChI=1S/C28H25F3N4O2/c1-14-6-15(8-17(32)7-14)19-4-5-33-13-25(19)35-28(37)20-2-3-22(29)21-9-16(12-34-27(20)21)26-23(30)10-18(36)11-24(26)31/h2-5,9-15,17,36H,6-8,32H2,1H3,(H,35,37)/t14-,15+,17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM376685 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)-c1c(F)cc(O)cc1F |r| Show InChI InChI=1S/C28H25F3N4O2/c1-14-6-15(8-17(32)7-14)19-4-5-33-13-25(19)35-28(37)20-2-3-22(29)21-9-16(12-34-27(20)21)26-23(30)10-18(36)11-24(26)31/h2-5,9-15,17,36H,6-8,32H2,1H3,(H,35,37)/t14-,15+,17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				Citation and Details BindingDB Entry DOI: 10.7270/Q20V8GZM
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM376685 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)-c1c(F)cc(O)cc1F |r| Show InChI InChI=1S/C28H25F3N4O2/c1-14-6-15(8-17(32)7-14)19-4-5-33-13-25(19)35-28(37)20-2-3-22(29)21-9-16(12-34-27(20)21)26-23(30)10-18(36)11-24(26)31/h2-5,9-15,17,36H,6-8,32H2,1H3,(H,35,37)/t14-,15+,17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 641-62 (2007) BindingDB Entry DOI: 10.7270/Q2MP55J7
					More data for this Ligand-Target Pair