Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM377193'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM377193 (5-Amino-N-{4-[(3S,5R)-3-amino-5-(trifluoromethyl)p...) Show SMILES N[C@H]1C[C@H](CN(C1)c1c2CCOc2ncc1NC(=O)c1nc(sc1N)-c1c(F)cccc1F)C(F)(F)F |r| Show InChI InChI=1S/C23H21F5N6O2S/c24-13-2-1-3-14(25)16(13)22-33-17(19(30)37-22)20(35)32-15-7-31-21-12(4-5-36-21)18(15)34-8-10(23(26,27)28)6-11(29)9-34/h1-3,7,10-11H,4-6,8-9,29-30H2,(H,32,35)/t10-,11+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Curacyte Chemistry GmbH					Assay Description Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 49: 4116-26 (2006) BindingDB Entry DOI: 10.7270/Q2FJ2K39
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM377193 (5-Amino-N-{4-[(3S,5R)-3-amino-5-(trifluoromethyl)p...) Show SMILES N[C@H]1C[C@H](CN(C1)c1c2CCOc2ncc1NC(=O)c1nc(sc1N)-c1c(F)cccc1F)C(F)(F)F |r| Show InChI InChI=1S/C23H21F5N6O2S/c24-13-2-1-3-14(25)16(13)22-33-17(19(30)37-22)20(35)32-15-7-31-21-12(4-5-36-21)18(15)34-8-10(23(26,27)28)6-11(29)9-34/h1-3,7,10-11H,4-6,8-9,29-30H2,(H,32,35)/t10-,11+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				Citation and Details BindingDB Entry DOI: 10.7270/Q2GB2776
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM377193 (5-Amino-N-{4-[(3S,5R)-3-amino-5-(trifluoromethyl)p...) Show SMILES N[C@H]1C[C@H](CN(C1)c1c2CCOc2ncc1NC(=O)c1nc(sc1N)-c1c(F)cccc1F)C(F)(F)F |r| Show InChI InChI=1S/C23H21F5N6O2S/c24-13-2-1-3-14(25)16(13)22-33-17(19(30)37-22)20(35)32-15-7-31-21-12(4-5-36-21)18(15)34-8-10(23(26,27)28)6-11(29)9-34/h1-3,7,10-11H,4-6,8-9,29-30H2,(H,32,35)/t10-,11+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation; Incyte Holdings Corporation US Patent					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μcompound/DMSO in the assa...				US Patent US10828290 (2020) BindingDB Entry DOI: 10.7270/Q2TB19Z5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM377193 (5-Amino-N-{4-[(3S,5R)-3-amino-5-(trifluoromethyl)p...) Show SMILES N[C@H]1C[C@H](CN(C1)c1c2CCOc2ncc1NC(=O)c1nc(sc1N)-c1c(F)cccc1F)C(F)(F)F |r| Show InChI InChI=1S/C23H21F5N6O2S/c24-13-2-1-3-14(25)16(13)22-33-17(19(30)37-22)20(35)32-15-7-31-21-12(4-5-36-21)18(15)34-8-10(23(26,27)28)6-11(29)9-34/h1-3,7,10-11H,4-6,8-9,29-30H2,(H,32,35)/t10-,11+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Holdings Corporation; Incyte Corporation US Patent					Assay Description Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.84 compound/DMSO in the assay buffer (...				US Patent US10517858 (2019) BindingDB Entry DOI: 10.7270/Q2XD1422
					More data for this Ligand-Target Pair