Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM50406888'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50406888 (CHEMBL4175950) Show SMILES CCOC(=O)c1nc2ccccc2nc1Nc1ccc2[nH]ccc2c1 Show InChI InChI=1S/C19H16N4O2/c1-2-25-19(24)17-18(23-16-6-4-3-5-15(16)22-17)21-13-7-8-14-12(11-13)9-10-20-14/h3-11,20H,2H2,1H3,(H,21,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Tours Curated by ChEMBL					Assay Description Inhibition of recombinant human Pim1 expressed in bacterial expression system using histone H1 as substrate after 30 mins by ADP-Glo reagent based lu...				Eur J Med Chem 154: 101-109 (2018) Article DOI: 10.1016/j.ejmech.2018.04.056 BindingDB Entry DOI: 10.7270/Q2HM5C0X
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