Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM50518519'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50518519 (CHEMBL4457389) Show SMILES CC1(CC#Cc2c(Cl)c3c(Cl)cc(nc3n2[C@H]2CCCNC2)C(N)=O)COC1 |r| Show InChI InChI=1S/C20H22Cl2N4O2/c1-20(10-28-11-20)6-2-5-15-17(22)16-13(21)8-14(18(23)27)25-19(16)26(15)12-4-3-7-24-9-12/h8,12,24H,3-4,6-7,9-11H2,1H3,(H2,23,27)/t12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Inhibition of PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser-112 residue by TR-FRET assay				Bioorg Med Chem Lett 29: 491-495 (2019) Article DOI: 10.1016/j.bmcl.2018.12.015 BindingDB Entry DOI: 10.7270/Q21V5J93
					More data for this Ligand-Target Pair