Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-2' and Ligand = 'BDBM162006'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM162006 (US9682991, 62) Show SMILES CNC1CCN(CC1)c1nn2c(nnc2c2OCCN(C)c12)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C21H24F3N7O2/c1-25-14-6-8-30(9-7-14)19-16-17(32-11-10-29(16)2)20-27-26-18(31(20)28-19)13-4-3-5-15(12-13)33-21(22,23)24/h3-5,12,14,25H,6-11H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-2 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
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