Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-2' and Ligand = 'BDBM238664'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238664 (US9394297, 326) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2nc(C)c(NC(C)(C)C)nc12 Show InChI InChI=1S/C20H23N5O/c1-10-16-13(19(26)22-10)9-15(23-16)12-7-6-8-14-17(12)24-18(11(2)21-14)25-20(3,4)5/h6-10,23H,1-5H3,(H,22,26)(H,24,25)/t10-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.559	n/a	n/a	n/a	n/a	7.0	22
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9394297 (2016) BindingDB Entry DOI: 10.7270/Q2G44P78
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238664 (US9394297, 326) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2nc(C)c(NC(C)(C)C)nc12 Show InChI InChI=1S/C20H23N5O/c1-10-16-13(19(26)22-10)9-15(23-16)12-7-6-8-14-17(12)24-18(11(2)21-14)25-20(3,4)5/h6-10,23H,1-5H3,(H,22,26)(H,24,25)/t10-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant Pim-2 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...				J Med Chem 59: 6407-30 (2016) Article DOI: 10.1021/acs.jmedchem.6b00610 BindingDB Entry DOI: 10.7270/Q2125X4G
					More data for this Ligand-Target Pair