Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-2' and Ligand = 'BDBM238715'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238715 (US9394297, 379) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1c(F)ccc2nc(C)c(NC3(C)CC3)nc12 Show InChI InChI=1S/C20H20FN5O/c1-9-16-11(19(27)23-9)8-14(24-16)15-12(21)4-5-13-17(15)25-18(10(2)22-13)26-20(3)6-7-20/h4-5,8-9,24H,6-7H2,1-3H3,(H,23,27)(H,25,26)/t9-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0484	n/a	n/a	n/a	n/a	7.0	22
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9394297 (2016) BindingDB Entry DOI: 10.7270/Q2G44P78
					More data for this Ligand-Target Pair