Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-2' and Ligand = 'BDBM238778'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238778 (US9394297, 465) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC1(C)CCC1)n(C)c2=O Show InChI InChI=1S/C21H23N5O2/c1-11-16-14(18(27)22-11)10-15(23-16)12-6-4-7-13-17(12)24-20(26(3)19(13)28)25-21(2)8-5-9-21/h4,6-7,10-11,23H,5,8-9H2,1-3H3,(H,22,27)(H,24,25)/t11-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.130	n/a	n/a	n/a	n/a	7.0	22
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9394297 (2016) BindingDB Entry DOI: 10.7270/Q2G44P78
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