Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-2' and Ligand = 'BDBM238810'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238810 (US9394297, 497) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2nc(C)c(N[C@H]3CCC[C@H](C3)NC(=O)[C@H](N)CO)nc12 Show InChI InChI=1S/C25H31N7O3/c1-12-21-17(24(34)28-12)10-20(31-21)16-7-4-8-19-22(16)32-23(13(2)27-19)29-14-5-3-6-15(9-14)30-25(35)18(26)11-33/h4,7-8,10,12,14-15,18,31,33H,3,5-6,9,11,26H2,1-2H3,(H,28,34)(H,29,32)(H,30,35)/t12-,14+,15-,18-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.160	n/a	n/a	n/a	n/a	7.0	22
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9394297 (2016) BindingDB Entry DOI: 10.7270/Q2G44P78
					More data for this Ligand-Target Pair