Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-2' and Ligand = 'BDBM50061602'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50061602 (CHEMBL3394166 | US9321756, 164) Show SMILES CCOc1cccc(n1)-c1c[nH]c2ccc(cc12)-c1nnc(N)s1 Show InChI InChI=1S/C17H15N5OS/c1-2-23-15-5-3-4-14(20-15)12-9-19-13-7-6-10(8-11(12)13)16-21-22-17(18)24-16/h3-9,19H,2H2,1H3,(H2,18,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	21.6	n/a	n/a	n/a	n/a	n/a	n/a
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9321756 (2016) BindingDB Entry DOI: 10.7270/Q2W094S2
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50061602 (CHEMBL3394166 | US9321756, 164) Show SMILES CCOc1cccc(n1)-c1c[nH]c2ccc(cc12)-c1nnc(N)s1 Show InChI InChI=1S/C17H15N5OS/c1-2-23-15-5-3-4-14(20-15)12-9-19-13-7-6-10(8-11(12)13)16-21-22-17(18)24-16/h3-9,19H,2H2,1H3,(H2,18,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM2 (unknown origin) using biotinylated-BAD peptide as substrate assessed as phosphorylation at serine 112 aft...				Bioorg Med Chem Lett 25: 775-80 (2015) Article DOI: 10.1016/j.bmcl.2014.12.091 BindingDB Entry DOI: 10.7270/Q2WQ05G8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50061602 (CHEMBL3394166 | US9321756, 164) Show SMILES CCOc1cccc(n1)-c1c[nH]c2ccc(cc12)-c1nnc(N)s1 Show InChI InChI=1S/C17H15N5OS/c1-2-23-15-5-3-4-14(20-15)12-9-19-13-7-6-10(8-11(12)13)16-21-22-17(18)24-16/h3-9,19H,2H2,1H3,(H2,18,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of PIM2 in human U2OS cells assessed as phosphorylation of BAD				Bioorg Med Chem Lett 25: 775-80 (2015) Article DOI: 10.1016/j.bmcl.2014.12.091 BindingDB Entry DOI: 10.7270/Q2WQ05G8
					More data for this Ligand-Target Pair