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Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-2' and Ligand = 'BDBM50517424'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase pim-2


(Homo sapiens (Human))		BDBM50517424
PNG
(CHEMBL4456165)
Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(c2=O)C1(C)CC1 |r|
Show InChI InChI=1S/C23H27N5O2/c1-12-17-15(19(29)24-12)11-16(25-17)13-7-6-8-14-18(13)26-21(27-22(2,3)4)28(20(14)30)23(5)9-10-23/h6-8,11-12,25H,9-10H2,1-5H3,(H,24,29)(H,26,27)/t12-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.160n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of full length recombinant PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...

J Med Chem 62: 1523-1540 (2019)


Article DOI: 10.1021/acs.jmedchem.8b01733
BindingDB Entry DOI: 10.7270/Q25X2D97
More data for this
Ligand-Target Pair