Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-3' and Ligand = 'BDBM106906'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM106906 (US8592455, 106) Show SMILES N[C@H]1CCC[C@H](C1)c1ccncc1NC(=O)c1nc(ccc1N)C1CCCCC1 |r| Show InChI InChI=1S/C23H31N5O/c24-17-8-4-7-16(13-17)18-11-12-26-14-21(18)28-23(29)22-19(25)9-10-20(27-22)15-5-2-1-3-6-15/h9-12,14-17H,1-8,13,24-25H2,(H,28,29)/t16-,17+/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of PIM3 kinase (unknown origin) using NH2-AGAGRSRHSSYPAGT-OH as substrate by kinase-Glo assay				J Med Chem 58: 8373-86 (2015) Article DOI: 10.1021/acs.jmedchem.5b01275 BindingDB Entry DOI: 10.7270/Q2H41VGN
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM106906 (US8592455, 106) Show SMILES N[C@H]1CCC[C@H](C1)c1ccncc1NC(=O)c1nc(ccc1N)C1CCCCC1 |r| Show InChI InChI=1S/C23H31N5O/c24-17-8-4-7-16(13-17)18-11-12-26-14-21(18)28-23(29)22-19(25)9-10-20(27-22)15-5-2-1-3-6-15/h9-12,14-17H,1-8,13,24-25H2,(H,28,29)/t16-,17+/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	7.5	n/a
Novartis AG US Patent					Assay Description The activity of PIM1, PIM2, and PIM3 is measured using a luciferase-luciferin based ATP detection reagent to quantify ATP depletion resulting from ki...				US Patent US8592455 (2013) BindingDB Entry DOI: 10.7270/Q2FF3R0C
					More data for this Ligand-Target Pair